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DeCS
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Descriptor English:
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Codon, Nonsense
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Descriptor Spanish:
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Codón sin Sentido
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Descriptor Portuguese:
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Códon sem Sentido
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Synonyms English:
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Codon, Termination, Premature
Codon, Unassigned
Mutation, Nonsense
Nonsense Codon
Nonsense Mutation
Premature Stop Codon
Unassigned Codon
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Tree Number:
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D13.444.735.544.355.250.235
G05.360.335.355.250.235
G05.365.590.195
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Definition English:
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An amino acid-specifying codon that has been converted to a stop codon (CODON, TERMINATOR) by mutation. Its occurance is abnormal causing premature termination of protein translation and results in production of truncated and non-functional proteins. A nonsense mutation is one that converts an amino acid-specific codon to a stop codon. |
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Indexing Annotation English:
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for amber or ochre suppressor mutations use SUPPRESSION, GENETIC
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History Note English:
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95
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Allowable Qualifiers English:
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Record Number:
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32304
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Unique Identifier:
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D018389
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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